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Disrupting the α-synuclein-ESCRT interaction with a peptide inhibitor mitigates neurodegeneration in preclinical models of Parkinson's disease.
Nat Commun. 2023 Apr 19;14(1):2150. doi: 10.1038/s41467-023-37464-2.
Nat Commun. 2023.
PMID: 37076542
Free PMC article.
Early-onset impairment of the ubiquitin-proteasome system in dopaminergic neurons caused by α-synuclein.
McKinnon C, De Snoo ML, Gondard E, Neudorfer C, Chau H, Ngana SG, O'Hara DM, Brotchie JM, Koprich JB, Lozano AM, Kalia LV, Kalia SK.
McKinnon C, et al. Among authors: ngana sg.
Acta Neuropathol Commun. 2020 Feb 14;8(1):17. doi: 10.1186/s40478-020-0894-0.
Acta Neuropathol Commun. 2020.
PMID: 32059750
Free PMC article.
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